Ceftriaxone: Difference between revisions

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* Ceftriaxone is used as the treatment for bacterial infections and is often used pre-operatively to reduce the risk of surgical infections
* Ceftriaxone is used as the treatment for bacterial infections and is often used pre-operatively to reduce the risk of surgical infections
'''INDICATIONS:'''
'''INDICATIONS:'''
* Open extremity fracture
* [[Extremity Injuries|Open extremity fracture]]
* Penetrating trauma to the torso
* [[Trunk Penetrating Injuries|Penetrating trauma to the torso]]
'''CONTRAINDICATIONS:'''
'''CONTRAINDICATIONS:'''
* Allergy to penicillin or cephalosporins
* Allergy to penicillin or cephalosporins
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* Allergic reaction
* Allergic reaction
'''DOSAGE AND ADMINISTRATION'''
'''DOSAGE AND ADMINISTRATION'''
* Using a standard 10 ml normal saline flush, waste approximately 0.5 ml of flush.  Attach needle to flush and inject into bottle of Ceftriaxone.  Swirl bottle to mix and draw back into flush syringe.  Inject IV or IM.
* IM - Using a standard 10 ml normal saline flush, waste 8 ml of flush.  Attach needle to flush and inject into bottle of Ceftriaxone.  Swirl bottle to mix and draw back into flush syringe.  Inject IM.
** Adult - 1g IV x1 dose.
** Adult - 1g IM x1 dose.
** Pediatric - 50mg/kg IV/IO up to 1g
** Pediatric - 50mg/kg IM up to 1g

Latest revision as of 12:39, 2 December 2025

Section 8 - MEDICATION GUIDELINES

ANTIBIOTIC

CEFTRIAXONE / ROCEPHIN

DESCRIPTION / ACTION:

  • Ceftriaxone is a third generation cephalosporin antibiotic that is used to treat bacterial infections
  • Ceftriaxone is used as the treatment for bacterial infections and is often used pre-operatively to reduce the risk of surgical infections

INDICATIONS:

CONTRAINDICATIONS:

  • Allergy to penicillin or cephalosporins
  • Administration of calcium containing medications

POSSIBLE ADVERSE REACTIONS

  • Diarrhea
  • Skin reactions (rash)
  • Allergic reaction

DOSAGE AND ADMINISTRATION

  • IM - Using a standard 10 ml normal saline flush, waste 8 ml of flush. Attach needle to flush and inject into bottle of Ceftriaxone. Swirl bottle to mix and draw back into flush syringe. Inject IM.
    • Adult - 1g IM x1 dose.
    • Pediatric - 50mg/kg IM up to 1g