Ketamine: Difference between revisions
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'''INDICATIONS''' | '''INDICATIONS''' | ||
* Sedation in the extremely agitated patient | * Sedation in the extremely agitated patient | ||
* Musculoskeletal Pain / Extremity Pain | |||
* Combative Post Resuscitation | |||
'''CONTRAINDICATIONS''' | '''CONTRAINDICATIONS''' | ||
* Hypersensitivity | * Hypersensitivity | ||
Latest revision as of 15:26, 15 December 2020
Section 8 - MEDICATION GUIDELINES
ANESTHETICS
Ketamine / Anesthetic
DESCRIPTION
- Dissociative anesthetic, Systemic. Schedule III controlled substance.
INDICATIONS
- Sedation in the extremely agitated patient
- Musculoskeletal Pain / Extremity Pain
- Combative Post Resuscitation
CONTRAINDICATIONS
- Hypersensitivity
- Penetrating eye injury.
- Pregnancy
- Due to sympathomimetic effects, contraindicated in patients with known, severe CAD (for example, patients currently experiencing STEMI).
PRECAUTIONS
- Have ventilatory support readily available
- There is no known antidote or reversal agent for Ketamine
- Emergence Reaction - Read "Special Note" at RxList - Ketamine
- If this occurs give Benzodiazepine.
- DIAZEPAM (VALIUM) 2 - 20 mg SLOW IVP or IM to desired effect.
- MIDAZOLAM (VERSED) 2 - 10 mg IV, IO or IN, titrated to effect.
- If this occurs give Benzodiazepine.
DOSAGE
- Titrate to effect, starting dose of 0.5 mg/kg slow IVP or 1 mg/kg IM.
Onset of action:
- IM administration: 3 – 5 minutes
- IV administration: 1- 2 minutes
Duration of action:
- 20 – 40 minutes when dosed at 4mg/kg IM.
- 12 – 20 minutes when dosed at 2mg/kg IV.
Side Effects:
- Hypertension, emesis, laryngospasm, tachycardia, bronchodilation, increased salivation, emergence reaction (12%).