Ceftriaxone

Section 8 - MEDICATION GUIDELINES

ANTIBIOTIC

CEFTRIAXONE / ROCEPHIN

DESCRIPTION / ACTION:

• Ceftriaxone is a third generation cephalosporin antibiotic that is used to treat bacterial infections
• Ceftriaxone is used as the treatment for bacterial infections and is often used pre-operatively to reduce the risk of surgical infections

INDICATIONS:

• Open extremity fracture
• Penetrating trauma to the torso

CONTRAINDICATIONS:

• Allergy to penicillin or cephalosporins
• Administration of calcium containing medications

POSSIBLE ADVERSE REACTIONS

• Diarrhea
• Skin reactions (rash)
• Allergic reaction

DOSAGE AND ADMINISTRATION

• IM - Using a standard 10 ml normal saline flush, waste 8 ml of flush. Attach needle to flush and inject into bottle of Ceftriaxone. Swirl bottle to mix and draw back into flush syringe. Inject IM.
  • Adult - 1g IM x1 dose.
  • Pediatric - 50mg/kg IM up to 1g