Adenosine

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Section 8 - MEDICATION GUIDELINES

ANTIARRHYTHMICS

Adenosine (ADENOCARD) / Antiarrhythmic

DESCRIPTION/ACTION:

  • It is a natural occurring agent that can "chemically cardiovert" Paroxysmal Supraventricular Tachycardia (PSVT) to a normal sinus rhythm.
  • It has a half-life of 5 seconds and does not cause hypotension like Verapamil.
  • Restores normal sinus rhythm by interrupting re-entrant pathways in the AV node.
  • Slows conduction time through the AV node.
  • Produces coronary artery vasodialation.

INDICATIONS:

CONTRAINDICATIONS:

  • 2nd and 3rd Degree Heart Block, Sick Sinus Syndrome, or known hypersensitivity to the medication.

PRECAUTIONS:

  • It may cause transient arrhythmias.
  • It may cause bronchospasm in asthma patients.
  • Heart transplant patients may only require a smaller dosage and patients on Theophylline based medications may require larger dosage, contact MEDICAL CONTROL for consult.

DOSAGE:

  • IV 12 mg by rapid IV bolus, if no results repeat 1-2 minutes later as 12 mg rapid IV bolus. Maximum total dose 24 mg.
  • Pediatrics - Refer to Handtevy System for patient specific dosage
    • Premies - 13 y/o: 0.1 mg/kg (1st dose), 0.2 mg/kg (2nd dose)
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