Ketamine: Difference between revisions

From Protocopedia
Jump to navigation Jump to search
(Created page with "==Section 8 - MEDICATION GUIDELINES== ===ANESTHETICS=== ====Ketamine / Anesthetic==== '''DESCRIPTION''' * Dissociative anesthetic, Systemic. Schedule III controlled substance...")
 
 
(4 intermediate revisions by the same user not shown)
Line 7: Line 7:
'''INDICATIONS'''
'''INDICATIONS'''
* Sedation in the extremely agitated patient
* Sedation in the extremely agitated patient
* Musculoskeletal Pain / Extremity Pain
* Combative Post Resuscitation
'''CONTRAINDICATIONS'''
'''CONTRAINDICATIONS'''
* Hypersensitivity
* Hypersensitivity
Line 17: Line 19:
* Emergence Reaction - Read "Special Note" at [https://www.rxlist.com/ketamine-hydrochloride-drug.htm RxList - Ketamine]  
* Emergence Reaction - Read "Special Note" at [https://www.rxlist.com/ketamine-hydrochloride-drug.htm RxList - Ketamine]  
** If this occurs give Benzodiazepine.
** If this occurs give Benzodiazepine.
*** [[Sedative Hypnotics|DIAZEPAM (VALIUM)]] 2 - 20 mg SLOW IVP or IM to desired effect.
*** [[Valium|DIAZEPAM (VALIUM)]] 2 - 20 mg SLOW IVP or IM to desired effect.
*** [[Sedative Hypnotics|MIDAZOLAM (VERSED)]] 2 - 10 mg IV, IO or IN, titrated to effect.
*** [[Versed|MIDAZOLAM (VERSED)]] 2 - 10 mg IV, IO or IN, titrated to effect.




'''DOSAGE'''
'''DOSAGE'''
* Dose is 2 mg/kg SLOW IVP OR 4 mg/kg IM, 1 dose
* Titrate to effect, starting dose of 0.5 mg/kg slow IVP or 1 mg/kg IM.


'''Onset of action:'''
'''Onset of action:'''

Latest revision as of 15:26, 15 December 2020

Section 8 - MEDICATION GUIDELINES

ANESTHETICS

Ketamine / Anesthetic

DESCRIPTION

  • Dissociative anesthetic, Systemic. Schedule III controlled substance.

INDICATIONS

  • Sedation in the extremely agitated patient
  • Musculoskeletal Pain / Extremity Pain
  • Combative Post Resuscitation

CONTRAINDICATIONS

  • Hypersensitivity
  • Penetrating eye injury.
  • Pregnancy
  • Due to sympathomimetic effects, contraindicated in patients with known, severe CAD (for example, patients currently experiencing STEMI).

PRECAUTIONS

  • Have ventilatory support readily available
  • There is no known antidote or reversal agent for Ketamine
  • Emergence Reaction - Read "Special Note" at RxList - Ketamine


DOSAGE

  • Titrate to effect, starting dose of 0.5 mg/kg slow IVP or 1 mg/kg IM.

Onset of action:

  • IM administration: 3 – 5 minutes
  • IV administration: 1- 2 minutes

Duration of action:

  • 20 – 40 minutes when dosed at 4mg/kg IM.
  • 12 – 20 minutes when dosed at 2mg/kg IV.

Side Effects:

  • Hypertension, emesis, laryngospasm, tachycardia, bronchodilation, increased salivation, emergence reaction (12%).